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Open Access Databases and Datasets for Drug Discovery
Open Access Databases and Datasets for Drug Discovery Timely resource discussing the future of data-driven drug discovery and the growing number of open-source databases With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers.The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated.The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data.The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases.The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.Contributed to and edited by experts with long-time experience in the field, Open Access Databases and Datasets for Drug Discovery includes information on: An extensive listing of open access databases and datasets for computer-aided drug designPubChem as a chemical database for drug discovery, DrugBank Online, and bioisosteric replacement for drug discovery supported by the SwissBioisostere databaseThe Protein Data Bank (PDB) and macromolecular structure data supporting computer-aided drug design, and the SWISS-MODEL repository of 3D protein structures and models PDB-REDO in computational aided drug design (CADD), and using Pharos/TCRD for discovering druggable targets Unmatched in scope and thoroughly reviewing small and large open data sources relevant for rational drug design, Open Access Databases and Datasets for Drug Discovery is an essential reference for medicinal and pharmaceutical chemists, and any scientists involved in the drug discovery and drug development.
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Discovery Prism
Divide light into colour instantly with this Discovery PrismMade from high quality plastic, this prism is a perfect addition to your science accessories. The 10cm optical prism divides white light into a colourful spectrum.The Discovery Prism comes
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Above Discovery
A collection that careens from Ancient Greece to the Klondike Gold Rush, for readers of A.S. Byatt and Margaret Atwood. “It is the part that is missing that I am drawn to, that I try to pin down.My gaze is always divided by what is here and what is no longer here.That, for me, is where the deepest pleasure lies, where the sweet overcomes the bitter."A couple coping with a recent loss are tasked with taking stock of a late biology enthusiast’s hoard.A support worker dedicated to rehabilitating young women suffering from, among other things, a certain unexpected effect of the climate apocalypse faces a truth that shatters the illusion separating her work and her personal life.An archaeologist formerly working in Syria struggles with her decision to flee from unrest, while the people she has left behind face an uncertain fate. In Jennifer Falkner’s richly imagined first collection, past and present glancingly converge, making the familiar outlines of myth, history, and everyday life seem suddenly strange.With spare, elegant prose, Falkner introduces the reader to those whose narratives are written in the language of empty space.Above Discovery is a stunning debut collection from an author to watch.
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Cuban Discovery
An island lost in time, Cuba is a decadent blend of romantic grandeur and off-beat Caribbean charm. Iconic 1950s automobiles parade through the seafront streets and rumba bars rub shoulders with centuries-old churches. Forested inland landscapes are home to tobacco plantations and rugged mountaintops, while swathes of white sand skirt the northern coast. On our tours of Cuba, we'll start in Havana before winding our way through the country, uncovering its treasures as we go - from Spanish colonial heritage to underground rivers.
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What is an old discovery?
An old discovery refers to a scientific or historical finding that was made a significant amount of time ago. These discoveries have often stood the test of time and have had a lasting impact on our understanding of the world. Examples of old discoveries include the theory of evolution by Charles Darwin, the discovery of electricity by Benjamin Franklin, and the invention of the printing press by Johannes Gutenberg. These discoveries have shaped our modern world and continue to be studied and celebrated for their significance.
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What was Luther's great discovery?
Luther's great discovery was the concept of justification by faith alone. He believed that individuals could be saved by their faith in God alone, rather than through good works or the sacraments of the Catholic Church. This idea challenged the traditional teachings of the Church and sparked the Protestant Reformation. Luther's emphasis on faith as the key to salvation had a profound impact on Christianity and led to the formation of new Protestant denominations.
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Series like Star Trek: Discovery
Series like Star Trek: Discovery are typically science fiction shows that explore themes of space exploration, advanced technology, and diverse alien cultures. They often feature a diverse cast of characters and focus on moral and ethical dilemmas faced by the crew. These series also tend to have high production values, intricate storylines, and a mix of action and drama. Fans of Star Trek: Discovery may enjoy other similar shows like The Expanse, Battlestar Galactica, and Doctor Who.
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What is your latest discovery?
My latest discovery is a new method for synthesizing a novel class of organic compounds with potential applications in drug development. By using a combination of computational modeling and organic synthesis techniques, my team and I were able to design and create these compounds with improved properties compared to existing ones. This discovery has the potential to open up new avenues for the development of more effective and targeted medications for various diseases.
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Namibian Discovery
In places starkly beautiful, in places packed with colourful life, Namibia is always ruled by Mother Nature. On this tour you’ll traverse the ever-changing ‘dune sea’ of the Namib desert. You’ll marvel at the fascinating planetary quirk that created the ‘Organ Pipes’ rock formation. You’ll get up close to the intriguing (possibly 1,000-year-old) Welwitschia Mirabilis plant. You’ll experience African safari thrills with giraffes, lions and zebras, and spot native birdlife from a champagne cruise off the Skeleton Coast. The best Namibia holidays offer an insider's insight, so you'll have an expert local tour manager with you throughout.
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Vietnamese Discovery
Travelling from high-energy cities to sleepy backwaters, ancient citadels to karst-dotted bays, our small-group Vietnam tours showcase everything that we love about this country. You’ll explore Hanoi’s labyrinthine Old Quarter and Ho Chi Minh City’s Parisian-style boulevards. You’ll help out on a rural farm and enjoy lunch with locals. You’ll sip salt coffee and sample rice paper snacks. And you’ll sail the serene waters of Halong Bay and Lan Ha Bay on an unforgettable 2-night cruise. Welcome to Vietnam…
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Dark Discovery
All Sam wants is a normal life, but her fur keeps getting in the way. Samantha survived an attack by shapeshifting coyotes that left her leg and life torn apart. As her body heals, she's dismayed to become part of the Shadows — people hiding their monstrous secrets from their neighbors and friends. A visit to a safe-house offers Sam the chance to learn to control her beast. When her friends' lives are at stake, Sam must face down her demons to come to the rescue. Can she learn to harness her new abilities, or will the monsters win after all?
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Dominic's Discovery
Dominic's middle name is trouble, but not because he's got a troublesome nature, but quite simply because he's ALWAYS in the wrong place at the wrong time.So it's not surprising that he's only allowed on the school trip to Thundercliff Bay - home to pirate legend, chilling ghost stories and lost treasure - by the skin of his teeth. Or that strict Mr Risley-Newsome, who has his beady eye on him, makes him stay at the youth hostel for forgetting his walking boots.What is surprising is that a very special discovery made by Dominic saves the day when the whole class is in serious danger, and proves to everyone that sometimes he can be in the right place at the right time.
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What was the gold discovery?
The gold discovery refers to the event in 1848 when gold was discovered at Sutter's Mill in California, sparking the California Gold Rush. The discovery led to a massive influx of people from all over the world seeking their fortunes in gold mining. This event had a significant impact on the development of California and the United States, as it led to rapid population growth and economic prosperity in the region.
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What kind of discovery is this?
This discovery is a significant scientific breakthrough in the field of astronomy. The detection of a new exoplanet, especially one that is potentially habitable, is a rare and exciting find. It opens up new possibilities for studying the potential for life beyond our solar system and deepens our understanding of the universe.
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What is the discovery of radioactivity?
The discovery of radioactivity is the phenomenon where certain elements spontaneously emit radiation in the form of particles or electromagnetic waves. This was first observed by Henri Becquerel in 1896 when he noticed that uranium salts emitted rays that could expose photographic plates. This discovery led to further research by Marie and Pierre Curie, who identified the elements polonium and radium as being radioactive. Radioactivity has since been found to have important applications in medicine, industry, and energy production.
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What is the Rossmann Discovery Tour?
The Rossmann Discovery Tour is a guided tour of the Rossmann pharmaceutical company's research and development facilities. During the tour, visitors have the opportunity to learn about the company's history, its innovative products, and the scientific processes involved in developing new medications. The tour provides a behind-the-scenes look at the inner workings of a pharmaceutical company and offers insights into the world of drug discovery and development. It is a unique opportunity for individuals interested in the pharmaceutical industry to gain a deeper understanding of how new medications are created.
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